Sithembiso Zwane was born in 1989 at Baragwanath Hospital situated in Soweto.
He completed his matric in 2008 and studied printmaking at Artist Proof Studio between 2009 -2010. In 2011 he started painting murals with Dancing Brushes, the company that he founded, and in 2014 he started to refocus on printmaking. He was selected in Sasol New Signatures TOP 100 and he was also one of the finalists in Thami Mnyele Art Awards. Zwane is interested in exploring different mediums, such as painting, pencil drawing and puppets. Zwane became an assistant printmaker at Prints on Paper.
Zwane is now a full-time artist in printmaking.